Role of Antioxidants in Male Infertility

The reproductive process in men (i.e. the production of millions of sperm cells) involves a great deal of oxidative energy which in turn generates high levels of reactive oxygen species (which can be likened to harmful 'waste products').

Studies have shown that male fertility and what’s called seminal quality have declined over the last few decades.

To combat the potentially harmful effects of the reactive oxygen species, the bodies of human males uses a number of antioxidant defence systems, namely vitamins A, C, E, coenzyme Q10, glutathione reductase and superoxide dismutase (vitamins and enzymes).

The role of free radicals is important in normal functioning and disease processes of human spermatozoa production.

Human sperm is very vulnerable to free radicals as their covering contains PUFA (Poly Unsaturated Fatty Acid) is easily destroyed by the existing peroxides. Therefore, high level of free radicals in our body can lead to infertility in men.

Free radicals (oxidative stress) are recognized as a primary cause for male infertility.

Normally, the semen is surrounded by several anti-oxidant enzymes like superoxide dismutase, glutathione peroxidase, catalase and reductase besides quite a few non-enzymatic antioxidants like alpha-tocopherol, ascorbate and urate.

They help the sperm to neutralize the damage caused by excess production of free radicals (oxidative stress) in our body.

In these cases, the main factor for infertility is recognized as over activity of free radicals rather than lowered action of antioxidants.

In a study done in 1997 involving male patients with primary infertility that addition of anti-oxidants in the form of beta-carotene, Vitamin C and Vitamin E together with the normal medication has improved the rate of conception by their female counterpart. The physiological parameters of spermatozoa have been improved.

Eating vegetables is good for your sperm. This is a good reason why men should be eating more vegetables.

Scientists from two fertility clinics in Spain have spent four years researching on the vegetables and fruits diet, at the same time the possible exposure to workplace contaminants in men with fertility problems. They are looking into the reproductive power of fruits and vegetables.

One of the groups examined the effects that antioxidants might have on sperm. The researchers hypothesized that antioxidants could lower the oxidative stress that can harm sperm. The researchers hypothesized that antioxidants could lower the oxidative stress that can harm sperm.

More antioxidants could theoretically improve both sperm concentration and motility.

The studies involved 61 men from couples with fertility problems. Thirty of the men were known to have sperm problems. The other 31 men acted as the control. Interviews revealed that the males with good semen quality ate significantly more fruits and vegetables. In general their diets were high in vitamins and antioxidants.

The study appears in the journal Fertility and Sterility. The researchers say this finding suggests that healthy diets lead to healthy sperm. So remember, guys, an apple a day keeps your swimmers in play.

Therefore, as a conclusion, it can be stated that spermatozoa are unable to withstand the oxidative stress and can cause male infertility. Adding antioxidants in conjunction with the normal mode of treatment is recommended.